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Interestingly, we observed a North-to-South decline of European gene flow in East Asians, suggesting a northern path of European gene flow diffusing into East Asian populations.Our findings contribute to an improved understanding of the history of human migration and the evolutionary mechanisms that have shaped the genetic structure of populations in Eurasia.

These studies reported the Asian or American contribution in European populations.

But the European gene flow in Asians has not been well studied yet.

In the current study, our samples did not cover all European regions.

For example, Southern European populations were not included in the analysis because they may have been affected by a recent genetic contribution from populations with African ancestry.

(b) Fine resolution of the PC plot after removing YRI.